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MRI Segmentation

Focused ultrasound therapy is a non-invasive treatment for breast cancer. An ultrasound transducer is used to heat a tumor to kill the undesired tissues. Planning a treatment requires a 3D MRI of the breast that has been segmented into tissue types, which is a very time-intensive process. Interobserver variability (differences between different individuals’ segmentations) can impact treatment plans.

Understanding how much this variability affects treatment planning is important to guiding what level of precision is needed in a segmentation for effective treatment planning. Once an MRI has been segmented, the segmentations themselves are compared, as well as results from both acoustic and thermal simulations of a proposed treatment plan.